The Leifer Institute for Molecular and Digital Pathology

The Leifer Institute for Molecular and Digital PathologyThe Leifer Institute for Molecular and Digital PathologyThe Leifer Institute for Molecular and Digital Pathology

(929) 269-7268

  • Home
  • History and Background
  • Projects Overview
  • Ligands
  • LigandsList
    • Outline
    • Tertiary Structure
    • Curvature
    • Supercoiling
    • LInear Length
    • Secondary Structure
    • Z-DNA
    • G-quadruplexes
    • i-motifs
    • Cruciform DNA
    • Triple Stranded DNA
    • Ligands and Mechanism
    • Binding to Bases
    • Intercalation
    • Enantiomers
    • Natural ligands
    • Metals
    • Antitumor Drugs
  • Pressure
  • Regulogenesis
  • 3D
  • Virtual Lab
  • Data Mining
  • Wiki Use
  • Gallery
  • More
    • Home
    • History and Background
    • Projects Overview
    • Ligands
    • LigandsList
      • Outline
      • Tertiary Structure
      • Curvature
      • Supercoiling
      • LInear Length
      • Secondary Structure
      • Z-DNA
      • G-quadruplexes
      • i-motifs
      • Cruciform DNA
      • Triple Stranded DNA
      • Ligands and Mechanism
      • Binding to Bases
      • Intercalation
      • Enantiomers
      • Natural ligands
      • Metals
      • Antitumor Drugs
    • Pressure
    • Regulogenesis
    • 3D
    • Virtual Lab
    • Data Mining
    • Wiki Use
    • Gallery

The Leifer Institute for Molecular and Digital Pathology

The Leifer Institute for Molecular and Digital PathologyThe Leifer Institute for Molecular and Digital PathologyThe Leifer Institute for Molecular and Digital Pathology

(929) 269-7268

  • Home
  • History and Background
  • Projects Overview
  • Ligands
  • LigandsList
  • Pressure
  • Regulogenesis
  • 3D
  • Virtual Lab
  • Data Mining
  • Wiki Use
  • Gallery

Pressure and Gene Regulation

There are many instances in  which  it has been observed that pressure on a cell can result in a change in gene expression. Mina Bissel's work. Melanomas on the ball and heel of the foot. Initial contact of bacterial cells with the surface during the early stage of biofilm formation.

We would like to study the mechanism of this stimulation. What happens between the pressure on the surface and the DNA-protein interaction that results in the stimulation or inhibition of transcription.

Find out more

Leifer Inst for Molecular and Digital Pathology

(929) 269-7268

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