The Leifer Institute for Molecular and Digital Pathology

The Leifer Institute for Molecular and Digital PathologyThe Leifer Institute for Molecular and Digital PathologyThe Leifer Institute for Molecular and Digital Pathology

(732) 415-8371

  • Home
  • History and Background
  • Projects Overview
  • Ligands
  • LigandsList
    • Outline
    • Tertiary Structure
    • Curvature
    • Supercoiling
    • LInear Length
    • Secondary Structure
    • Z-DNA
    • G-quadruplexes
    • i-motifs
    • Cruciform DNA
    • Triple Stranded DNA
    • Ligands and Mechanism
    • Binding to Bases
    • Intercalation
    • Enantiomers
    • Natural ligands
    • Metals
    • Antitumor Drugs
  • Pressure
  • MCS
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  • Regulogenesis
  • 3D
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  • Foldscope
  • Gallery
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  • Slide 10
  • More
    • Home
    • History and Background
    • Projects Overview
    • Ligands
    • LigandsList
      • Outline
      • Tertiary Structure
      • Curvature
      • Supercoiling
      • LInear Length
      • Secondary Structure
      • Z-DNA
      • G-quadruplexes
      • i-motifs
      • Cruciform DNA
      • Triple Stranded DNA
      • Ligands and Mechanism
      • Binding to Bases
      • Intercalation
      • Enantiomers
      • Natural ligands
      • Metals
      • Antitumor Drugs
    • Pressure
    • MCS
      • Introduction
      • Research
      • Articles
      • Videos
      • Resources
    • Regulogenesis
    • 3D
    • Virtual Lab
    • Data Mining
    • Wiki Use
    • Foldscope
    • Gallery
    • Personal
      • Publications
    • Slide 10

The Leifer Institute for Molecular and Digital Pathology

The Leifer Institute for Molecular and Digital PathologyThe Leifer Institute for Molecular and Digital PathologyThe Leifer Institute for Molecular and Digital Pathology

(732) 415-8371

  • Home
  • History and Background
  • Projects Overview
  • Ligands
  • LigandsList
    • Outline
    • Tertiary Structure
    • Curvature
    • Supercoiling
    • LInear Length
    • Secondary Structure
    • Z-DNA
    • G-quadruplexes
    • i-motifs
    • Cruciform DNA
    • Triple Stranded DNA
    • Ligands and Mechanism
    • Binding to Bases
    • Intercalation
    • Enantiomers
    • Natural ligands
    • Metals
    • Antitumor Drugs
  • Pressure
  • MCS
    • Introduction
    • Research
    • Articles
    • Videos
    • Resources
  • Regulogenesis
  • 3D
  • Virtual Lab
  • Data Mining
  • Wiki Use
  • Foldscope
  • Gallery
  • Personal
    • Publications
  • Slide 10

Triple stranded dna

  Ligand: N-[2-(dimethylamino)ethyl]-2-(2-naphthyl)quinolin-4-yl-amine

Effect on DNA structure: Increases the formation of triple stranded DNA

Reference(s): Brown, P.M., Drabble, A. and Fox, K.R. Effect of a Triplex-Binding Ligand on Triple Helix Formation at a Site Within a Natural DNA Fragment.
Biochemical Journal 314:427-432 (1996)
http://www.biochemj.org/content/314/2/427


 

Leifer Inst for Molecular and Digital Pathology

(732) 415-8371

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