The Leifer Institute for Molecular and Digital Pathology

The Leifer Institute for Molecular and Digital PathologyThe Leifer Institute for Molecular and Digital PathologyThe Leifer Institute for Molecular and Digital Pathology

(732) 415-8371

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  • Ligands
  • LigandsList
    • Outline
    • Tertiary Structure
    • Curvature
    • Supercoiling
    • LInear Length
    • Secondary Structure
    • Z-DNA
    • G-quadruplexes
    • i-motifs
    • Cruciform DNA
    • Triple Stranded DNA
    • Ligands and Mechanism
    • Binding to Bases
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    • Home
    • History and Background
    • Projects Overview
    • Ligands
    • LigandsList
      • Outline
      • Tertiary Structure
      • Curvature
      • Supercoiling
      • LInear Length
      • Secondary Structure
      • Z-DNA
      • G-quadruplexes
      • i-motifs
      • Cruciform DNA
      • Triple Stranded DNA
      • Ligands and Mechanism
      • Binding to Bases
      • Intercalation
      • Enantiomers
      • Natural ligands
      • Metals
      • Antitumor Drugs
    • Pressure
    • MCS
      • Introduction
      • Research
      • Articles
      • Videos
      • Resources
    • Regulogenesis
    • 3D
    • Virtual Lab
    • Data Mining
    • Wiki Use
    • Foldscope
    • Gallery
    • Personal
      • Publications
    • Slide 10

The Leifer Institute for Molecular and Digital Pathology

The Leifer Institute for Molecular and Digital PathologyThe Leifer Institute for Molecular and Digital PathologyThe Leifer Institute for Molecular and Digital Pathology

(732) 415-8371

  • Home
  • History and Background
  • Projects Overview
  • Ligands
  • LigandsList
    • Outline
    • Tertiary Structure
    • Curvature
    • Supercoiling
    • LInear Length
    • Secondary Structure
    • Z-DNA
    • G-quadruplexes
    • i-motifs
    • Cruciform DNA
    • Triple Stranded DNA
    • Ligands and Mechanism
    • Binding to Bases
    • Intercalation
    • Enantiomers
    • Natural ligands
    • Metals
    • Antitumor Drugs
  • Pressure
  • MCS
    • Introduction
    • Research
    • Articles
    • Videos
    • Resources
  • Regulogenesis
  • 3D
  • Virtual Lab
  • Data Mining
  • Wiki Use
  • Foldscope
  • Gallery
  • Personal
    • Publications
  • Slide 10

z-dna

ligands that change B-DNA to Z-DNA

12

Ligand:    Aklavin


Effect on DNA Structure:  Changes B-DNA to Z-DNA


Reference(s):  

Hur, J.H., Lee, A-R. , Yoo, W., Lee, J-H. and Kim, K.K.  Identification of a new 

Z-DNA inducer Usinng SYBR Green 1 as a DNA Conformation Sensor

FEBS Letters  593 (18): 2628-2636 (2019)

 https://doi.org/10.1002/1873-3468.13513 



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Leifer Inst for Molecular and Digital Pathology

(732) 415-8371

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